The need-to-know information for Ranitidine (Zantac)Ranitidine
Pearls and Fun Nuggets
1. Ranitidine used to be the used for long term management of acid reflux 🍕However, proton-pump inhibitors (PPIs) have taken over this role.
2. Ranitidine has recently been recalled 😳In September 2019, the U.S. Food and Drug Administration (FDA) learned that some ranitidine medicines, including some products sold under the brand name Zantac, contained a nitrosamine impurity called N-nitrosodimethylamine (NDMA), classified as a probable human carcinogen, at low levels. Some products have since been recalled, but no immediate threat from Ranitidine has been identified.
3. It might drop your vitamin B12 😐 Elderly patients taking H2 receptor antagonists are more likely to require supplementation than those not taking such drugs.
4. It might also reduce the absorption of other drugs 😯 This is because some drugs require an acidic stomach to absorb correctly (azole antifungals, calcium carbonate). H2 blockers tend to reduce stomach acid.
5. Ranitidine might make you pop hot on a drug test 😅 It’s known for occasionally creating false positives for methamphetamine on some commercial drug kits.
“I’ve been on Ranitidine for almost 2 years it work great for heartburn, I take before food and it did reduce the bloat. But currently it has been recall….any suggestions on the replacement drug or any brand still available”
“After 9 months of horrible psychotic-type itching I finally was able to see a dermatologist who I believe has correctly identified the cause. He believes I have eczema. The stress level following a whole spine surgery probably caused the condition to surface and begin its damage. I started taking Benadryl on my own and it helped a lot. When he added the H2 blocker (Zantac) it has all but disappeared. Wonderful! Thank you so much!”
“This medication works well for me, if I take the prescription strength twice a day, everyday. Unlike many drugs in the same class, Zantac provides relief within thirty minutes to an hour. This, thus far, has worked for me. Please consult your medical provider for a treatment designed for you.”