The need-to-know information for PrimaquinePrimaquine
Pearls and Fun Nuggets
1. Primaquine is usually taken during the last 1-2 weeks of other malaria treatment. It’s primarily used to prevent relapse of malaria due to Plasmodium vivax and Plasmodium ovale. It eliminates hypnozoites, the dormant liver form of the parasite, after the organisms have been cleared from the bloodstream.
2. If you don’t take it, beware the consequences 😳 If primaquine is not administered to patients with proven P. vivax or P. ovale infection, a very high likelihood of relapse exists for weeks or months (sometimes years).
3. Primaquine has been around for a while 📰 Primaquine was first made by Robert Elderfield of Columbia University in the 1940s as part of a coordinated effort led by the Office of Scientific Research and Development in World War II to develop anti-malarial drugs to protect and treat soldiers fighting in the Pacific theater.
4. Be careful not to take too much 💊 Overdosing can reduce the number of function of various kinds of blood cells, including loss of red blood cells, methemoglobinemia, and loss of white blood cells.
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