The need-to-know information for Malarone


Pearls and Fun Nuggets

1. Malarone doesn’t work every time 😔 Some malaria strains are resistant to atovaquone/proguanil.

2. Take it with a hamburger 🍔 It must be taken with a fatty meal, or at least some milk, for the body to absorb it adequately—and to avoid painful stomach irritation, which proguanil frequently causes if taken without food.

3. Malarone isn’t the best for severe cases 👎 Atovaquone/proguanil is not normally used to treat severe malaria, when an injectable drug such as quinine is used instead.

4. Malarone is a little pricey 💸The cost for Malarone oral tablet (250 mg-100 mg) is around $182 for a supply of 24 tablets,

Patient Perspectives

“I found this drug tough to handle and have one more day to go. I took this for a trip to Peruvian Amazon. I and another traveler had sleep problems taking it at night. That was remedied by taking it with full fat yogurt after breakfast. However I have had days of nausea and stomach cramps. I am assuming after I finish the post Amazon 7-day course, I will return to normal. Tougher than I expected. I know many people who have taken his drug with no ill effects. Just depends on your constitution.”


“Took for 10 days for a 3 day visit to Kruger National Park. Was totally bricking it after readying all the scare stories. Zero side effects. No nausea, no weird dreams, nothing. Took with breakfast, including dairy.”


“I was so scared to take these after all the bad reviews. I was in South Africa with a group and we were 8 people taking malarone and we were all without side effects luckily. We always took the tablet after eating and only for 14 days. but it was all fine :)”

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